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pentobarbital will lower the extent or result of quetiapine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.Keep an eye on Closely (one)pentobarbital will lower the level or outcome of tofacitinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. Loss of, or decreased reaction to tofac